EFFECT OF PHENTOLAMINE ON THE METABOLIC RESPONSE TO GYNAECOLOGICAL SURGERY

Open Access

1 May 1982

journal article
research article
Published by Elsevier in British Journal of Anaesthesia

Vol. 54 (5) , 517-521
https://doi.org/10.1093/bja/54.5.517

Abstract

The effect of the infusion of phentolamine 0.5 mg min⁻¹ on the metabolic response to gynaecological surgery was investigated. In comparison with a control group of patients, phentolamine was associated with a significant increase in plasma insulin concentration after 30 and 60 min of surgery. The glycaemic response to surgery was decreased by α-adrenergic blockade, but this was only significant after 120 min of surgery. The hypotension produced by the administration of phentolamine was well tolerated.

Keywords

PHENTOLAMINE
GYNECOLOGIC SURGICAL PROCEDURES
SURGICAL PROCEDURES
OPERATIVE
SURGERY SPECIALTY
INFUSION PROCEDURES
INSULIN
PLASMA
HYPOTENSION

This publication has 1 reference indexed in Scilit:

CARDIOSELECTIVE (METOPROLOL) AND NON-SELECTIVE (PROPRANOLOL) BETA-BLOCKADE AND GLUCOSE HOMEOSTASIS
1977