Lacrimal immunoglobulins and complement quantified by counter-immunoelectrophoresis.
Open Access
- 1 May 1975
- journal article
- research article
- Published by BMJ in British Journal of Ophthalmology
- Vol. 59 (5) , 279-281
- https://doi.org/10.1136/bjo.59.5.279
Abstract
Immunoglobulin and complement concentrations of tears were measured using a sensitive electroimmunodiffusion assay. In the 13 subjects tested, the predominant immunoglobulin was secretory IgA (mean concentration 107 mug/mg protein; standard error of mean 15; n equal 17). The B1C component of complement was measurable in half of the subjects studied. The data illustrate that it is possible to quantify exactly certain humoral indices which may be important in the host defense of the eye.Keywords
This publication has 10 references indexed in Scilit:
- Quantitative determinations of complement components and immunoglobulins in tears and aqueous humor.1974
- In vitro synthesis of immunoglobulins, secretory component and complement in normal and pathological skin and the adjacent mucous membranes.1973
- Immunoglobulins in TearsAmerican Journal of Ophthalmology, 1973
- Immunoglobulins in the Human EyeArchives of Ophthalmology (1950), 1973
- Salivary Immunoglobulins in Sjögren's SyndromeInternational Archives of Allergy and Immunology, 1972
- Quantitative estimation of protein by electroimmunodiffusion on Cellogel acetate membranes.Journal of Clinical Pathology, 1971
- Demonstration and characterization of antibody in tears following intranasal vaccination with inactivated type 13 rhinovirus: a preliminary report.1970
- Immunoglobulins in Human TearsAmerican Journal of Ophthalmology, 1969
- Synthesis in vitro of immunoglobulins produced by different human mucous membranesCellular and Molecular Life Sciences, 1969
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951