Effects of Vitamin B12 on Diethylstilbestrol and Thyroprotein Action in Male Rats.

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Abstract
The effects of crystalline vit. B12 on several actions of diethylstilbestrol and thyroprotein were detd. in 100 young male albino rats. Diethylstilbestrol and thyroprotein were incorporated into the ration in amts. of 0.1 and 0.16%, respectively, and vit. B12 was injected subcut. in doses of 0.2 or 0.4 [mu]g. daily. Vit. B12 partially counteracted. the growth-retarding action of these 2 hormones when given individually or together, and also increased food consumption. The vitamins did not alter the ability of diethylstilbestrol or thyroprotein to depress testes weight or the ability of the former to increase the wt. of the seminal vesicles.

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