Localisation of immunoglobulin on the liver cell surface in primary biliary cirrhosis
Open Access
- 1 October 1981
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 34 (10) , 1076-1079
- https://doi.org/10.1136/jcp.34.10.1076
Abstract
Direct immunofluorescence studies were performed on isolated liver cells in order to detect surface localisation of IgG in acute and chronic hepatitis and primary biliary cirrhosis. Membrane-bound IgG was demonstrated in nine patients. Six of eight patients with primary biliary cirrhosis showed granular fluorescence on their liver cell surfaces suggesting that an antibody or immune complex-mediated cytotoxicity might be involved in the pathogenesis of this disease.This publication has 15 references indexed in Scilit:
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