DNAs of the Two Mating-Type Alleles of Neurospora crassa Are Highly Dissimilar
- 29 July 1988
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 241 (4865) , 570-573
- https://doi.org/10.1126/science.2840740
Abstract
The mating-type alleles A and a of Neurospora crassa control mating in the sexual cycle and function in establishing heterokaryon incompatibility in the vegetative cycle. The A and a alleles were cloned, and they were shown to encode both the sexual functions and vegetative incompatibility. The mating-type clones contain nonhomologous DNA segments that are flanked by common DNA sequences. Neurospora crassa and all heterothallic and pseudohomothallic Neurospora species contain a single copy of one mating-type sequence or the other within each haploid genome. The six known self-fertile homothallic isolates contain an A homolog, but only one species also contains a homologous sequences. Homothallism in these species is not due to mating-type switching, as it is in Saccharomyces cerevisiae.This publication has 19 references indexed in Scilit:
- Transcriptional Regulation in the Yeast Life CycleScience, 1987
- Determination of the yeast cell lineageCell, 1987
- Neurospora discreta, a new heterothallic species defined by its crossing behaviorExperimental Mycology, 1986
- Efficient cloning of genes of Neurospora crassaProceedings of the National Academy of Sciences, 1986
- Identification and chromosomal distribution of 5S rRNA genes in Neurospora crassa.Proceedings of the National Academy of Sciences, 1985
- A technique for radiolabeling DNA restriction endonuclease fragments to high specific activityAnalytical Biochemistry, 1983
- NULL MUTANTS OF THEAANDaMATING TYPE ALLELES OFNEUROSPORA CRASSACanadian Journal of Genetics and Cytology, 1982
- Structure and organization of transposable of transposable mating type cassettes in Saccharomyces yeasts.Proceedings of the National Academy of Sciences, 1980
- Strains of Neurospora Collected from NatureEvolution, 1976
- HETEROCARYOSIS AND PROTOPLASMIC INCOMPATIBILITY IN NEUROSPORA CRASSAProceedings of the National Academy of Sciences, 1956