Stereoselective Alkylation of Lithium Enolates Generated from t-Butyl Esters of 4-Alkyl-Substituted 5-Hydroxypentanoic Acids
- 1 February 1988
- journal article
- Published by Oxford University Press (OUP) in Bulletin of the Chemical Society of Japan
- Vol. 61 (2) , 571-573
- https://doi.org/10.1246/bcsj.61.571
Abstract
Alkylation of lithium enolates generated from t-butyl esters of 4-alkyl-substituted 5-hydroxypentanoic acid by treatment with lithium pyrrolidinide in THF–HMPA proceeded stereoselectively to afford the corresponding anti-α-alkylated esters.This publication has 4 references indexed in Scilit:
- Selective 1,4-Chiral Induction in the Reaction of Enolates Generated from t-Butyl δ-Hydroxy CarboxylatesBulletin of the Chemical Society of Japan, 1987
- A new synthesis of δ-lactones from oxetanesTetrahedron Letters, 1984
- The ester enolate Claisen rearrangement. Stereochemical control through stereoselective enolate formationJournal of the American Chemical Society, 1976
- The Relative Stabilities of cis and trans Isomers. IV. The 3,5-Dimethylcycloheptanones1,2Journal of the American Chemical Society, 1959