Anti-EGFR monoclonal antibodies which act as EGF, TGFα, HB-EGF and BTC antagonists block the binding of epiregulin to EGFR-expressing tumours
- 19 January 1998
- journal article
- Published by Wiley in International Journal of Cancer
- Vol. 75 (2) , 310-316
- https://doi.org/10.1002/(sici)1097-0215(19980119)75:2<310::aid-ijc22>3.0.co;2-f
Abstract
No abstract availableKeywords
This publication has 17 references indexed in Scilit:
- Epiregulin binds to epidermal growth factor receptor and ErbB-4 and induces tryosine phosphorylation of epidermal growth factor receptor, ErbB-2, ErbB-3 and ErbB-4Oncogene, 1997
- Activation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferationThe EMBO Journal, 1997
- Epidermal Growth Factor-related Peptides Activate Distinct Subsets of ErbB Receptors and Differ in Their Biological ActivitiesJournal of Biological Chemistry, 1996
- Phase I trial and tumour localisation of the anti-EGFR monoclonal antibody ICR62 in head and neck or lung cancerBritish Journal of Cancer, 1996
- Type 1 growth factor receptors: an overview of recent developmentsThe Breast, 1995
- Heterodimerization and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer researchBreast Cancer Research and Treatment, 1995
- Immunotherapy with antibodies to the EGF receptorInternational Journal of Cancer, 1994
- The human EGF receptor as a target for cancer therapy: six new rat mAbs against the receptor on the breast carcinoma MDA-MB 468British Journal of Cancer, 1993
- The Physiology Of Transforming Growth Factor-αAdvances in Cancer Research, 1992
- MDA-468, a human breast cancer cell line with a high number of epidermal growth factor (EGF) receptors, has an amplified EGF receptor gene and is growth inhibited by EGFBiochemical and Biophysical Research Communications, 1985