Depletion of Esterified Cholesterol in Mouse Testes and Leydig Cell Tumors by Luteinizing Hormone1

Abstract
LH (50 μg) given sc to normal mice and Leydig cell tumor bearing mice promoted a decrease in the content of esterified cholesterol in the testes of normal mice and in the tumor. The observation that LH promoted a change in the tumor ester cholesterol levels was interpreted to mean that its action on testicular ester levels was probably on the interstitial cells. (Endocrinology91: 323, 1972

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