Folic Acid Deficiency in the Duck

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Abstract
Folic acid deficiency has been produced in ducklings and is characterized by reduced growth rate, only slightly reduced food consumption, macrocytic anemia, enlarged liver, and a lowered titer of trypsin and amylase activity in the duodenal contents. The liver from the deficient bird is low in glycogen and slightly high in fat and in total nitrogen content. Blood glucose is normal. Under the experimental conditions employed, no interrelationship was found between folic acid and vitamin B12. Histopathological examination of deficient tissue showed absence of the secretory cycle of zymogen granules in the pancreas, decreased alkaline phosphatase in the liver, and blurring of striation in the heart.

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