Radioimmunoassayable methotrexate concentrations in plasma and skin exudate of patients with psoriasis
- 1 December 1979
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical and Experimental Dermatology
- Vol. 4 (4) , 457-463
- https://doi.org/10.1111/j.1365-2230.1979.tb01641.x
Abstract
Summary: Radioimmunoassay is a rapid, convenient, specific and sensitive method of measuring methotrexate (MTX) levels in plasma and skin exudate. Chronic users have a delayed peak level compared to recently treated patients. MTX levels in skin exudate approximate to those in plasma. Only 50% of plasma MTX is free, whereas almost all is free in skin exudate.This publication has 3 references indexed in Scilit:
- Development and application of a radioimmunoassay for methotrexateBritish Journal of Cancer, 1977
- A new method for recovery of exudates from normal and inflamed human skin*Clinical and Experimental Dermatology, 1977
- Assay of Therapeutic Doses of Methotrexate in Body Fluids of Patients with PsoriasisJournal of Investigative Dermatology, 1975