Cohort study of relation between donating blood and risk of myocardial infarction in 2682 men in eastern finland

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Abstract
We investigated the incidence of acute myocardial infarctions in participants in the Kuopio ischaemic heart disease risk factor study.3 During 1984-9 we carried out baseline examinations of 2682 (83%) of the 3235 men aged 42, 48, 54, or 60 whom we had invited. We obtained data on the subjects' donating blood by record linkage to files of the local Red Cross office. We registered and verified all myocardial infarctions, definite or possible, between the baseline examinations and the end of 1992.2 The mean follow up time was 5.5 years, and, with multiple infarctions, we considered only the first. We used Cox's proportional hazard's analyses to compare the occurrence of cardiac events in blood donors and in non-donors.

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