Failure of ketoconazole in cryptococcal meningitis
- 25 June 1982
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 247 (24) , 3349-3351
- https://doi.org/10.1001/jama.247.24.3349
Abstract
Ketoconazole was used to treat an indolent case of cryptococcal meningitis that had not completely responded to a course of standard therapy with amphotericin B and flucytosine. Despite treatment with 600 mg/day of ketoconazole for 7 mo. and adequate serum and CSF concentrations, the patient suffered a relapse while still receiving the drug. After the relapse, the condition responded to a higher-than-standard dose course of amphotericin B and flucytosine.This publication has 2 references indexed in Scilit:
- Successful Treatment of Cerebral Cryptococcoma and Meningitis with MiconazoleAnnals of Internal Medicine, 1980
- Amphotericin B in Cryptococcal MeningitisAnnals of Internal Medicine, 1969