Hemoproteins in Microsomes in Liver of Tumor-bearing Rats*
- 1 December 1965
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Biochemistry
- Vol. 58 (6) , 595-598
- https://doi.org/10.1093/oxfordjournals.jbchem.a128248
Abstract
Cytochrome b5 and P-450 in microsomes, and catalase were analysed in the liver of normal and rats bearing Rhodamine sarcoma, methylcholanthrene sarcoma, ascites hepatomas AH 130 or AH 66 F. In the liver of all animals bearing any one of tumors, the liver catalase activity was depressed. Significant decreases in cytochrome b5 and P-450 level were observed in the liver bearing AH 66 F or methylcholanthrene sarcoma. This is the first case of the depression of hemoprotein in the liver of tumor-bearing animals other than catalase.This publication has 2 references indexed in Scilit:
- EFFECT OF BACTERIAL CONTAMINATION OF TUMOR ON TUMOR-HOST RELATIONSHIPS1963
- A Chemical Basis for Tumor-Host RelationsJNCI Journal of the National Cancer Institute, 1960