Escherichia coli ribosomal RNA transcription: regulatory roles for ppGpp, NTPs, architectural proteins and a polymerase‐binding protein
Open Access
- 12 January 2005
- journal article
- review article
- Published by Wiley in Molecular Microbiology
- Vol. 55 (4) , 973-977
- https://doi.org/10.1111/j.1365-2958.2004.04455.x
Abstract
Ribosomal RNA transcription can limit the rate of Escherichia coli growth and is subject to complex regulation. Somehow, the cell is able to sense the general nutritional environment and adjust rRNA transcription so that an appropriate number of ribosomes is produced. This review discusses the current state of affairs, including recent information about the involvement of two nucleotide regulators, two architectural protein regulators, one new co‐regulator and stalled ribosomes.Keywords
This publication has 34 references indexed in Scilit:
- Nucleotide-Dependent Isomerization of Escherichia coli RNA PolymeraseBiochemistry, 2004
- Mechanism of Stimulation of Ribosomal Promoters by Binding of the +1 and +2 NucleotidesPublished by Elsevier ,2004
- Growth Phase-Dependent Regulation and Stringent Control of fis Are Conserved Processes in Enteric Bacteria and Involve a Single Promoter ( fis P) in Escherichia coliJournal of Bacteriology, 2004
- The distribution of RNA polymerase in Escherichia coli is dynamic and sensitive to environmental cuesMolecular Microbiology, 2003
- Structural Basis for H-NS-mediated Trapping of RNA Polymerase in the Open Initiation Complex at the rrnB P1Journal of Biological Chemistry, 2002
- Nucleoid Proteins Stimulate Stringently Controlled Bacterial Promoters: A Link between the cAMP-CRP and the (p)ppGpp Regulons in Escherichia coliCell, 2000
- The G+C-rich discriminator region of the tyrT promoter antagonises the formation of stable preinitiation complexesJournal of Molecular Biology, 2000
- The bacterial DNA-binding protein H-NS represses ribosomal RNA transcription by trapping RNA polymerase in the initiation complexJournal of Molecular Biology, 2000
- Invariance of the Nucleoside Triphosphate Pools ofEscherichia coli with Growth RatePublished by Elsevier ,2000
- Effects of the Escherichia coli DNA‐binding protein H‐NS on rRNA synthesis in vivoMolecular Microbiology, 1998