Water suppression with B0 field gradient homospoil pulses in high‐resolution NMR spectroscopy

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Abstract
The combination of a frequency nonselective excitation suppression method (1331 sequence) with selective excitation followed by gradient‐induced dephasing of water transverse magnetization yielded suppression ratios of greater than 10,000:1. The need for gradient preemphasis and correction of Bo field shifts is discussed. The suppression efficiency of this method compared favorably to results obtained using the CPMG spin‐ echo technique to observe metabolite resonances in a urine sample. © 1989 Academic Press, Inc.