Homograft Target Cells: Specific Destruction in vitro by Contact Interaction with Immune Macrophages
- 25 September 1964
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 145 (3639) , 1427-1429
- https://doi.org/10.1126/science.145.3639.1427
Abstract
Specific adherence and mutual immunologic destruction occurred after contact in vitro of immune peritoneal macrophages from C57BI/6K mice with homograft target cells from A/Jax mice. Cell destruction apparently resulted from a nonphagocytic mechanism involving cell contact rather than humoral antibody. Cell destruction was determined by a plaque technique with either immunecells or target cells as monolayers.Keywords
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