AMMONIA FORMATION AND GLUTAMIG ACID IN BRAIN TISSUE
- 1 March 1955
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Biochemistry
- Vol. 42 (2) , 131-139
- https://doi.org/10.1093/oxfordjournals.jbchem.a126515
Abstract
During the incubation of brain homogenate of guinea pig there occurred NH3 formation, which was accompanied by a decrease in glutamic acid content as well as an increase in glutamine; the adenylic compounds determined by UV spectrophotometry at neighborhood of a260 m[mu]. was scarcely changed. Yield of NH3 was slightly reduced by the addition of 10-3 [image] inosinic and muscle adenylic acids, but considerably increased by inosinetriphosphate. In conclusion, glutamic acid is considered to be a predominant precursor of NH3 in brain tissue under the present condition.This publication has 10 references indexed in Scilit:
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