Transforming growth factors—an overview

Publisher Website
Google Scholar
Abstract
Transforming Growth Factors (TGFs) are a sub‐group of a larger family of protein hormones. Two major types of TGF are currently known, alpha‐TGF and beta‐TGF. Biologically their most important property is to act synergistically to induce anchorage‐independent growth of target cells otherwise incapable of such growth. Since this growth parameter is well correlated with tumorigenicity in vivo, these factors may play a role in cancer development. Biochemically both alpha‐TGF and beta‐TGF have been well characterised in some types of cells and tissues. Their role in normal and neoplastic growth is actively studied.

This publication has 0 references indexed in Scilit: