Allocortical involvement in Huntington's disease
- 1 December 1992
- journal article
- Published by Wiley in Neuropathology and Applied Neurobiology
- Vol. 18 (6) , 539-547
- https://doi.org/10.1111/j.1365-2990.1992.tb00824.x
Abstract
Seven brains of individuals who had suffered from Huntington's disease and seven control brains were examined. Preparations stained for Nissl material and lipofuscin pigment revealed a characteristic layer‐specific loss of nerve cells in two allocortical areas, the entorhinal region and the subiculum. The most severe changes occurred in the entorhinal layer Pri‐y while layer Pre‐a, layer Pre‐y and the subiculum showed less severe alterations.Keywords
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