Galactorrhea Due to Imipramine

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Abstract
NONPUERPERAL galactorrhea has previously been reported in association with administration of various drugs, including reserpine1 2 3 and chlorpromazine.4 5 6 7 Although imipramine (Tofranil) and reserpine have certain pharmacologic effects in common, galactorrhea has not been cited as a complication of imipramine therapy. In the case reported below galactorrhea occurred during treatment with imipramine.Case ReportA 34-year-old woman was seen because of spontaneous galactorrhea. Her only pregnancy had terminated in abortion 4 years previously. Since that time the menses had occurred every 27 to 35 days. Three years before, a diagnosis of hypothyroidism had been made; the plasma protein-bound iodine level was 2.3 . . .