Gene conversion: observations on the DNA hybrid models
- 1 February 1970
- journal article
- research article
- Published by Hindawi Limited in Genetics Research
- Vol. 15 (1) , 55-64
- https://doi.org/10.1017/s0016672300001373
Abstract
SUMMARY: Some features of gene conversion in fungi and their bearing on the hybrid DNA models are discussed. Available experimental data from tetrad analysis seem to give a more complex picture of polarity in intra-genic recombination and of the relations between conversion and post-meiotic segregation, and between conversion and crossing-over, than predicted by the models.A new hypothesis of the mechanism of gene conversion with special attention given to the aspect of asymmetry in this phenomenon is proposed as an alternative to the mechanism suggested by the DNA hybrid models.Keywords
This publication has 23 references indexed in Scilit:
- An Evaluation of the Relationship Between Ultraviolet Sensitivity and Crossing-Over in Bacteria and FungiThe American Naturalist, 1969
- DNA RepairAnnual Review of Biochemistry, 1968
- A study on simultaneous conversions in linked genes in Ascobolus immersusGenetics Research, 1967
- An Operator Model of Crossing-OverNature, 1966
- The analysis of genetic recombination on the polaron hybrid DNA modelGenetics Research, 1965
- Genetic control of DNA breakdown and repair inE. coli K-12 treated with mitomycin C or ultraviolet lightMolecular Genetics and Genomics, 1964
- A Polaron Model of Genetic Recombination by the Formation of Hybrid Deoxyribonucleic AcidNature, 1964
- A Theory of Crossing-Over by Means of Hybrid Deoxyribonucleic AcidNature, 1963
- Genetics of Sordaria fimicola. V. Aberrant Segregation at the G LocusAmerican Journal of Botany, 1962
- Three Kinds of Transreplication in Sordaria fimicolaThe Japanese Journal of Genetics, 1962