Amphiphilic Network as Nanoreactor for Enzymes in Organic Solvents
- 4 December 2004
- journal article
- Published by American Chemical Society (ACS) in Nano Letters
- Vol. 5 (1) , 45-48
- https://doi.org/10.1021/nl048413b
Abstract
Enzymes are powerful biocatalysts that work naturally in water but are also active in organic solvents. Here, we present a nanophase-separated amphiphilic network, where an enzyme is entrapped into its hydrophilic domains. A substrate that diffuses into the other, hydrophobic, phase of such a network can access the biocatalyst via the extremely large interface. Entrapped horseradish peroxidase and chloroperoxidase showed dramatically increased activity and operational stability compared to the native enzymes.Keywords
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