The Crisis in Clinical Cancer Research

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Abstract
Clinical cancer research is in jeopardy. Current budgetary constraints on federal support for biomedical research, the escalating costs of health care delivery, and the recent refusal of some third-party payers to support the costs of patient care as part of research trials threaten to compromise clinical investigations that might lead to progress in the treatment of cancer.This situation has arisen despite advances over the past four decades that have led to curative therapy for childhood leukemia, Hodgkin's disease, non-Hodgkin's lymphoma, cancer of the testis, and many solid tumors in children. Clinical research has also substantially reduced mortality among premenopausal . . .