Translocation 21q22q in an infertile human male

1 October 1982

journal article
research article
Published by BMJ in Journal of Medical Genetics

Vol. 19 (5) , 366-369
https://doi.org/10.1136/jmg.19.5.366

Abstract

Details are given of a balanced 21q22q Robertsonian translocation ascertained through infertility in a phenotypically normal male. Chromosome analyses on the proband and his parents showed that the translocation arose as a new mutation. The patient was oligospermic and had a high frequency of morphological abnormalities in his spermatozoa. Meiotic investigations showed a chain trivalent in all primary spermatocytes examined at diakinesis/metaphase I. The testicular histology was normal.

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