HLA Markers in Six Lebanese Religious Subpopulations

Abstract
A total of 315 normal, unrelated individuals from 6 [Maronites, Catholic Greeks, Orthodox Greeks, Armenians, Sunnites and Shiites] of the 7 principal religious communities of Lebanon were typed for 26 alleles of the HLA-A and HLA-B loci. The gene, haplotype frequencies and delta values were calculated. The HLA gene frequencies for A and B loci crossed Moslem-Christian lines, but a distinguishably different profile for the Armenian immigrant subpopulation was seen. This first-level homogeneity, which is inconsistent with results earlier reported for ABO, Rhesus and Gm systems, seems to disappear when linkage disequilibrium deltas are compared.

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