PHYSIOLOGICAL VARIATIONS IN THE CARDIAC OUTPUT OF MAN

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Abstract
(III). The changes in the pulse rate, blood pressure, O consumption and cardiac output were studied in 6 subjects after the ingestion of light and heavy meals. After the ingestion of food, the pulse rate rises; but it falls again to the resting value within a short time. The systolic blood pressure usually rises about 8 mm. while the diastolic pressure remains constant or falls slightly. The pulse pressure is, therefore, but slightly increased. The cardiac output rises immediately after the ingestion of food reaches a maximum of 0.5 to 2.0 1. over the fasting level, and remains at this high and practically constant level for 1 to 3 hrs. Four or 5 hrs. after the ingestion of a light meal the cardiac output has returned to its fasting level. The arterio-venous O difference after meals may remain unchanged or drop somewhat. (IV). Psychic disturbances were found to increase the cardiac output from 0.1 (in the case of mild disturbances) to 0.91. (in the case of anger). The pulse and blood pressure showed concomitant increases, while the O consumption was also slightly increased. Mild disturbances, not accompanied by pulse or blood pressure changes, produced no change in the cardiac output. As regards the mechanism of the circulatory changes following psychic disturbances, the results indicate that there are other factors, besides vasomotor reactions, which affect the vascular system in emotional changes.

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