COMPARISON OF A NEW AMINOGLYCOSIDE (G-418) AND GENTAMICIN FOR TREATMENT OF SWINE-DYSENTERY IN SWINE NATURALLY INFECTED WITH SALMONELLA-CHOLERAESUIS
- 1 January 1977
- journal article
- research article
- Vol. 38 (9) , 1293-1297
Abstract
The addition of the aminoglycosidic antibiotic, G-418, to drinking water at the concentration of 37.5 mg/l for 3 days was effective in treatment of experimentally induced swine dysentery in swine. With this concentration, there was a recession of diarrhea during or immediately after withdrawal of medication. The diarrhea recurred .apprx. 2 wk after medication was stopped. With the concentration of 12.5 mg of G-418/l given to swine for 3 days, the diarrhea did not recede during or after medication. With the concentration of 12.5 mg of gentamicin/l given to swine for 3 days, the diarrhea receded in some swine during and after medication, but more swine died in the medicated exposed groups than died in the nonmedicated exposed groups. Both drugs appeared to be effective against the concurrent spontaneous infection of S. cholerae-suis in the swine used in the study.This publication has 3 references indexed in Scilit:
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- STUDIES ON PORCINE ENTERITIS .2. EXPERIMENTAL THERAPY WITH SULFATHALIDINE, SULFAMETHAZINE, SODIUM ARSANILATE, AND BACITRACIN IN A NATURAL OUTBREAK OF SWINE DYSENTERY1951