Use of the Radionuclide Washout Test in Evaluation of Suspected Upper Urinary Tract Obstruction

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Abstract
The use of the computerized quantitative renal scan associated with the standard renogram obtained during furosemide-induced diuresis provides useful information in the assessment of suspected upper tract obstruction. With the use of 99mtechnetium diethylenetriaminepentaacetic acid or 131iodine hippuran quantitative renal scans were obtained and renograms were generated before and after i.v. furosemide injection. Rapidity of diuretic-induced radionuclide washout, as well as determination of glomerular filtration rate of effective renal plasma flow on the affected side, provides objective information with regard to renal parenchymal loss as well as upper tract emptying. Experience with 19 patients is reported. The radionuclide washout test is easily obtained, informative and may replace more invasive diagnostic measures.