Stereodivergent synthesis of two diastereoisomeric enoates by asymmetric horner–wadsworth–emmons reaction using a single chiral auxiliary
- 1 January 1994
- journal article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 18,p. 2167-2168
- https://doi.org/10.1039/c39940002167
Abstract
Stereodivergent synthesis of both diastereoisomeric enoates, including vinylogous acids, is achieved in the kinetic resoultion of branched aldehydes and asymmetrization of prochiral cyclic ketone by chiral phosphorus reagents derived from (–)-8-phenylmenthol.Keywords
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