Chemical transformation of rat cells infected with xenotropic type-C RNA virus and its suppression by virus-specific antiserum.
- 1 February 1977
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 74 (2) , 579-581
- https://doi.org/10.1073/pnas.74.2.579
Abstract
Fischer rat embryo cells infected with xenotropic mouse type-C RNA viruses isolated from NIH Swiss or C57L inbred mice were transformed by 4-nitroquinoline oxide or 3-methylcholanthrene under conditions in which neither treatment alone sufficed to induce transformation. Transformation was dependent on the presence of actively growing virus at the time of chemical treatment. Specific antibody to xenotropic virus neutralized the virus and inhibited malignant transformation by 3-methylcholanthrene.This publication has 12 references indexed in Scilit:
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