Abstract
There is now available a sound theoretical background to the study of gene frequency changes in natural populations, and this is due in great measure to the mathematical models devised by Professor Sir Ronald Fisher, Professor J. B. S. Haldane and Professor S. Wright. This mathematical approach tells us what will happen in any particular set of circumstances under the conditions laid down for the model, but it does not show us whether the model, in fact, represents the situation found in nature. However, as a result of a combination of theoretical studies, field work and experimental investigations, it is now generally agreed that the division of a species into a number of partly or temporarily isolated populations of various sizes gives the conditions most likely to result in rapid evolution. Nevertheless, the details of the processes involved are still in dispute.

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