THE IMPLANTATION OF NEO-NATAL PANCREAS INTO THE CHEEK POUCH OF THE ALLOXAN DIABETIC HAMSTER

Publisher Website
Google Scholar
Abstract
Neo-natal hamster pancreas, in which beta-cells were just beginning to differentiate, was implanted into the cheek pouches of both normal and alloxan-diabetic hamsters. It was found that: among the diabetics, 90% of the implants“took” while 75%“took” in the non-diabetics; the implants grew 30% larger and persisted 50% longer in diabetics than in normals; there was evidence for considerably more beta differentiation in the diabetic than in normals. Among the diabetics, where the graft persisted, blood sugars returned to the normal range and the pancreas of the host showed normal histology within two weeks of time the implants were made. Both of these latter events are considered rare for this particular post-alloxan period.

This publication has 2 references indexed in Scilit: