Growth of Leishmania donovani Amastigotes in a Continuous Macrophage‐Like Cell Culture*
- 1 August 1979
- journal article
- research article
- Published by Wiley in The Journal of Protozoology
- Vol. 26 (3) , 453-456
- https://doi.org/10.1111/j.1550-7408.1979.tb04652.x
Abstract
The feasibility of using a macrophage-like murine tumor cell as a host for L. donovani was investigated. This cell line, designated P388D1, rapidly phagocytized amastigotes and supported their intracellular replication. It can serve as a model host without the inherent limitations of primary macrophage cultures.Keywords
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