Quantitation of human thymus/leukemia-associated antigen by radioimmunoassay in different forms of leukemia
Open Access
- 1 December 1979
- journal article
- Published by American Society of Hematology in Blood
- Vol. 54 (6) , 1400-1406
- https://doi.org/10.1182/blood.v54.6.1400.1400
Abstract
Using a radioimmunoassay, increased levels of a human thymus/leukemia- associated antigen (HThy-L) have been detected in leukemic cells and plasma from most patients with E-rosette-positive acute lymphoblastic leukemia (ALL) and a number of patients with E-rosette-negative ALL, acute myeloblastic leukemia (AML), acute monomyelocytic leukemia (AMML), and acute undifferentiated leukemia (AVL). Low levels of HThy-L have been demonstrated in white cells from patients with chronic myelocytic leukemia (stable phase) and in mononuclear cells from patients with chronic lymphatic leukemia. The relationship between HThy- L and differentiation of hematopoietic cells is discussed.Keywords
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