Detecting Single Porphyrin Molecules in a Conically Shaped Synthetic Nanopore
- 26 July 2005
- journal article
- research article
- Published by American Chemical Society (ACS) in Nano Letters
- Vol. 5 (9) , 1824-1829
- https://doi.org/10.1021/nl050925i
Abstract
We report here the first example of abiotic resistive-pulse sensing of a molecular (as opposed to a particle or macromolecular) analyte. This was accomplished by using a conically shaped nanopore prepared by the track-etch method as the sensing element. It is possible to sense the molecular analyte because the small diameter opening of the conical nanopore (∼4.5 nm) is comparable to the diameter of the analyte molecule (∼2 nm).Keywords
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