The Enzymatic Conversion of (-)-Lupinine to (-)-(trans-4'-Hydroxycinnamoyl) lupinine by Extracts of Lupinus Seedlings

Abstract
(-)-(trans-4'-Hydroxycinnamoyl) lupinine (III) was found to be synthesized from (-)-lupinine (I) and trans-4-hydroxycinnamic acid (II) by enzymes in Lupinus seedlings in the presence of adenosine triphosphate and co-enzyme A as cofactors. The conversion of trans-cinnamic acid (IV) to (-)-(trans-cinnamoyl) lupinine (V) by the enzyme systems was negligible although the cinnamoyl-CoA ligase activity was clearly observed.

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