PULMONARY VENO-OCCLUSIVE DISEASE

  • 1 January 1975
    • journal article
    • research article
    • Vol. 44  (173) , 133-159
Abstract
In pulmonary veno-occlusive disease there is a widespread occlusion of the pulmonary veins and venules by a loose intimal fibrosis which is often basophilic. Recanalization of the occluded veins is common. These occlusive lesions in the pulmonary veins lead to an elevation of pulmonary arterial pressure with associated disease of these vessels, and are also responsible for chronic edema of the alveolar walls with subsequent development of interstitial pulmonary fibrosis. In a 16 yr old girl organized thrombi were present in the pulmonary arteries in addition to the pulmonary venous lesions.