Drug-induced Malabsorption

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Abstract
1. The history and relevance of drug-induced malabsorption are reviewed. 2. The tests used to assess intestinal structure and function in man are briefly described. 3. Neomycin, the most potent cause of drug-induced malabsorption, is reviewed in detail. It disturbs small bowel histology, impairs the absorption of actively absorbed substances normally measured in function tests and lowers the serum cholesterol. 4. Each test of intestine absorption is considered separately and the drugs which modify them are discussed. Where possible, the mechanisms of action are described.