Primary pulmonary hypertension, Castleman's disease and human herpesvirus‐8
- 1 September 2003
- journal article
- case report
- Published by European Respiratory Society (ERS) in European Respiratory Journal
- Vol. 22 (3) , 403-407
- https://doi.org/10.1183/09031936.03.00006903
Abstract
Primary pulmonary hypertension (PPH) and Castleman's disease (CD) are rare conditions infrequently encountered in clinical practice.In this paper, two patients diagnosed with both of these diseases are reported. The authors speculate that rather than being a chance occurrence, these conditions are linked by a common angio-proliferative mechanism. Therefore, an association between infection with the human herpesvirus‐8 and the diseases of PPH and CD was sought.Evidence of human herpesvirus‐8 infection was found in the lung tissue and, specifically, in the plexiform lesions from one of the patients.Keywords
This publication has 22 references indexed in Scilit:
- Assessment of a Combined Testing Strategy for Detection of Antibodies to Human Herpesvirus 8 (HHV-8) in Persons with Kaposi's Sarcoma, Persons with Asymptomatic HHV-8 Infection, and Persons at Low Risk for HHV-8 InfectionJournal of Clinical Microbiology, 2002
- THE PATHOBIOLOGY OF PULMONARY HYPERTENSION: EndotheliumClinics in Chest Medicine, 2001
- Primary Pulmonary HypertensionCirculation, 2000
- Elongation Factor-1α Is a Novel Substrate of Rho-Associated KinaseBiochemical and Biophysical Research Communications, 2000
- Increased Expression of Vascular Endothelial Growth Factor (VEGF) in Castleman's Disease: Proposed Pathomechanism of Vascular Proliferation in the Affected Lymph NodeLeukemia & Lymphoma, 2000
- The Clinical Behavior of Localized and Multicentric Castleman DiseaseAnnals of Internal Medicine, 1998
- Pulmonary Hypertension in POEMS SyndromeAmerican Journal of Respiratory and Critical Care Medicine, 1998
- Monoclonal endothelial cell proliferation is present in primary but not secondary pulmonary hypertension.Journal of Clinical Investigation, 1998
- Vascular Endothelial Growth Factor in Pulmonary HypertensionAnnals of the New York Academy of Sciences, 1996
- Prevalence of Kaposi's sarcoma associated herpesvirus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigenThe Lancet, 1996