Therapy of Experimental Herpes Simplex Keratitis in Rabbits with 5-lodo-5'-Amino-2',5'-Dideoxyuridine

Abstract
AIU (5-iodo-5''-amino-2'',5''-dideoxyuridine, AIdUrd) was shown to be as effective as IdUrd [idoxuridine] in the treatment of experimental herpes simplex keratitis in rabbits. AIU''s striking lack of cellular or systemic toxicity or teratogenicity and its specific inhibition of viral metabolism are discussed.

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