Human follicular fluid: Prolactin is biologically active and ovum fertilization correlates with estradiol concentration
- 1 June 1988
- journal article
- conference paper
- Published by Springer Nature in Journal of Assisted Reproduction and Genetics
- Vol. 5 (3) , 129-133
- https://doi.org/10.1007/bf01131174
Abstract
The bioactivity of prolactin (PRL) in follicular fluid (FF) obtained from mature preovulatory follicles was measured by the Nb2 lymphoma-cell bioassay and compared with the immunoreactivity as measured by radioimmunoassay (RIA-PRL). There was a good correlation between the two assay systems (P2) concentration of FF obtained from follicles that contained oocytes which were subsequently fertilized was greater than that in follicles containing oocytes which were not fertilized: 588±62 vs 376±37 ng/ml (P<0.01), respectively. No differences were found in bioassay-PRL, RIA-PRL, progesterone (P), and FF volumes between fertilized and unfertilized groups of follicles. FF from mature preovulatory follicles contained greater concentrations of RIA-PRL compared to immature follicles (34.6±3.1 vs 8.5±1.6 ng/ml; P<0.001).This publication has 16 references indexed in Scilit:
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