A Specific Cutaneous Reaction in Persons Infected with the Virus of Herpes Simplex

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Abstract
Summary: When a heated inactivated preparation of herpes simplex virus is inoculated intracutaneously in herpetic persons a specific erythematous reaction is produced. A positive intracutaneous reaction is regularly correlated with the presence of circulating antibody against herpes virus. An instance of primary herpetic infection in an adult is reported.