Transformation to Aggressive B-cell Lymphoma
- 1 September 2003
- journal article
- research article
- Published by Wolters Kluwer Health in Applied Immunohistochemistry & Molecular Morphology
Abstract
Many indolent lymphomas are destined for eventual transformation to aggressive B-cell lymphomas, an event with significant impact on therapy and outcome. Specific morphologic patterns of transformation are described for common subtypes of low-grade B-cell lymphoma. The discussion highlights immunophenotypic, molecular, and genetic characteristics of lymphoma transformation.Keywords
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