CUTANEOUS CHANGES IN LUPUS ERYTHEMATOSUS

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Abstract
A REVIEW of lupus erythematosus has been presented in numerous papers.1 The present paper deals with the cutaneous histopathologic aspects of lupus erythematosus, with special reference to the vascular changes within the cutis. It will include a review of the literature directly pertaining to the subject. REVIEW OF THE LITERATURE Although the histopathologic changes within the epidermis are secondary to changes within the cutis, they are nevertheless considered to be of great diagnostic significance.2 The changes within the epidermis consist in hyperkeratosis without parakeratosis, keratotic plugging of the hair follicles and glandular orifices and, independent of the foregoing, atrophy and adjacent acanthosis of the rete mucosa and liquefaction degeneration of the basal cell layer. The histopathologic changes within the cutis are variable; so far as subacute disseminated lupus erythematosus and acute disseminated lupus erythematosus are concerned, there are divergent opinions regarding the interpretation of these changes. Edema
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