The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME–Tox)
Top Cited Papers
- 1 May 2008
- journal article
- review article
- Published by Elsevier in Drug Discovery Today
- Vol. 13 (9-10) , 379-393
- https://doi.org/10.1016/j.drudis.2007.12.010
Abstract
No abstract availableKeywords
This publication has 98 references indexed in Scilit:
- Structure and mechanism of ABC transporter proteinsCurrent Opinion in Structural Biology, 2007
- Evidence for a Sav1866‐like architecture for the human multidrug transporter P‐glycoproteinThe FASEB Journal, 2007
- Cholesterol Potentiates ABCG2 Activity in a Heterologous Expression System: Improved in Vitro Model to Study Function of Human ABCG2The Journal of Pharmacology and Experimental Therapeutics, 2007
- Increased??Absorption??of??Digoxin from??the??Human??Jejunum Due??to??Inhibition??of??Intestinal Transporter-Mediated EffluxClinical Pharmacokinetics, 2007
- Targeting multidrug resistance in cancerNature Reviews Drug Discovery, 2006
- Substrate-induced Conformational Changes in the Transmembrane Segments of Human P-glycoproteinPublished by Elsevier ,2003
- Clinical Relevance of P-Glycoprotein in Drug TherapyDrug Metabolism Reviews, 2003
- Functional Characterization of the Human Multidrug Transporter, ABCG2, Expressed in Insect CellsBiochemical and Biophysical Research Communications, 2001
- Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.Journal of Clinical Investigation, 1995
- Transmembrane Aromatic Amino Acid Distribution in P-glycoproteinJournal of Molecular Biology, 1994