Is familial combined hyperlipidaemia a genetic disorder of adipose tissue?
- 1 April 1997
- journal article
- review article
- Published by Wolters Kluwer Health in Current Opinion in Lipidology
- Vol. 8 (2) , 89-94
- https://doi.org/10.1097/00041433-199704000-00006
Abstract
Familial combined hyperlipidaemia is a common cause of coronary heart disease. Its aetiology is heterogeneous. The genetic and metabolic basis of the disorder has not yet been defined. This review discusses the putative role of adipose tissue in the pathogenesis of familial combined hyperlipidaemia. It is possible that mutations in genes regulating the turnover of lipids in fat cells are involved in the aetiology.Keywords
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