The mechanism by which dietary AGEs are a risk to human health is via their interaction with RAGE: Arguing against the motion

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Abstract
We are interested in the regulation of intracellular calcium and the various diseases associated with an altered regulation of this second messenger. More recently, we also became interested in pathologies involving the Ca2+‐binding S100 proteins and AGEs and their association with the multifunctional Receptor for Advanced Glycation Endproducts (RAGE). Introduction: http://dx.doi.org/10.1002/mnfr.200700017 Pro arguments: http://dx.doi.org/10.1002/mnfr.200700008
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  • Nestec