Depsipeptide (FR901228, NSC-630176) pharmacokinetics in the rat by LC/MS/MS
- 1 September 1997
- journal article
- research article
- Published by Springer Nature in Investigational New Drugs
- Vol. 15 (3) , 195-206
- https://doi.org/10.1023/a:1005847703624
Abstract
Depsipeptide, a cyclic peptide (FR), isolated from Chrombacterium violaceum strain WB968 by Fujisawa Company during a screening program for anti-oncogene agents, possesses potent antitumor activity...Keywords
This publication has 14 references indexed in Scilit:
- FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. III. Antitumor activities on experimental tumors in mice.The Journal of Antibiotics, 1994
- FR901228, a novel antitumor bicyclic depsipeptide produced by chromobacterium violaceum No. 968. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties, and antitumor activity.The Journal of Antibiotics, 1994
- The sensitive determination of abanoquil in blood by high-performance liquid chromatography/atmospheric pressure ionization mass spectrometryJournal of Mass Spectrometry, 1992
- Determination of L-365,260, a new cholecystokinin receptor (CCK-B) antagonist, in plasma by liquid chromatography/atmospheric pressure chemical ionization mass spectrometryJournal of Mass Spectrometry, 1992
- Quantitative analysis by high-performance liquid chromatography atmospheric pressure chemical ionization mass spectrometry: The determination of the renin inhibitor CP-80,794 in human serumJournal of the American Society for Mass Spectrometry, 1991
- Passive and Carrier-Mediated Intestinal Absorption Components of CaptoprilJournal of Pharmaceutical Sciences, 1988
- Identification and quantitation of alcophosphamide, a metabolite of cyclophosphamide, in the rat using chemical ionization mass spectrometryJournal of Mass Spectrometry, 1987
- Pharmacokinetic Analysis of Concentration Data of Drugs with Irregular Absorption Profiles Using Multi-Fraction Absorption ModelsJournal of Pharmaceutical Sciences, 1987
- Clinical Pharmacokinetics of CyclosporinClinical Pharmacokinetics, 1986
- THE EFFECT OF FOOD ON CYCLOSPORINE ABSORPTIONTransplantation, 1985