Binding of oestradiol to blood proteins and aetiology of breast cancer
- 14 November 1986
- journal article
- research article
- Published by Wiley in International Journal of Cancer
- Vol. 38 (5) , 625-630
- https://doi.org/10.1002/ijc.2910380502
Abstract
A prospective study of 5,000 women has shown that, compared to controls, those who subsequently developed breast cancer had a higher proportion of their blood oestradiol in the non-protein-bound and albumin-bound fractions (the bio-available fraction) and a lower proportion in the sex-hormone-bound fraction. The increased proportion of bio-available oestradiol was partly due to a lower concentration of sex-hormone-binding globulin. Weight was excluded as a confounding factor.This publication has 23 references indexed in Scilit:
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