Recurrent Granulomatous Dermatitis with Eosinophilia.
- 1 April 1984
- journal article
- case report
- Published by Wiley in International Journal of Dermatology
- Vol. 23 (3) , 198-202
- https://doi.org/10.1111/j.1365-4362.1984.tb04511.x
Abstract
A 27-year-old woman developed a chronic, recurrent eruption of the face and upper extremities with the clinical and histopathologic features of recurrent granulomatous dermatitis with eosinophilia (Wells'syndrome). As described in 15 previously reported cases, this disorder is characterized by two clinical phases (ensinophilic cellulitis and granuloniatou plaque phase) and three histopathologic stages. The latter are particularly remarkable for a diffuse dermal and subcutaneous eosinophilia in acute lesions and scattered flame figures in chronic lesions. Distinctive findings in this case were the predominance of facial involvement and the symptomatic response to topical corticosteroids. Although etiology and pathogenesis are unknown, we feel that Wells'syndrome is a unique yet rarely recognized clinicopathologic entityKeywords
This publication has 6 references indexed in Scilit:
- Eosinophilic cellulitis. (Well's syndrome) in a childArchives of Dermatology, 1981
- EOSINOPHILIC CELLULITIS-A RESPONSE TO TREATMENT WITH DAPSONE: CASE REPORTAustralasian Journal of Dermatology, 1980
- Wells' syndrome. Recurrent granulomatous dermatitis with eosinophiliaArchives of Dermatology, 1979
- Eosinophilic cellulitis—persistent cutaneous swelling with phagocytosis of eosinophilic debrisBritish Journal of Dermatology, 1978
- Cold Urticaria: Release into the Circulation of Histamine and Eosinophil Chemotactic Factor of Anaphylaxis during Cold ChallengeNew England Journal of Medicine, 1976
- Demonstration of Immune Complexes in Spontaneous and Histamine-Induced Lesions and in Normal Skin of Patients with Leukocytoclastic AngiitisJournal of Investigative Dermatology, 1975